Praziquantel: A Review
نویسندگان
چکیده
منابع مشابه
Praziquantel, Mefloquine-Praziquantel, and Mefloquine-Artesunate-Praziquantel against Schistosoma haematobium: A Randomized, Exploratory, Open-Label Trial
BACKGROUND Treatment and morbidity control of schistosomiasis relies on a single drug, praziquantel. Hence, there is a pressing need to develop additional therapeutics against schistosomiasis. The antimalarial drug mefloquine shows antischistosomal activity in animal models and clinical trials, which calls for further investigations. METHODOLOGY We comparatively assessed the efficacy and tole...
متن کاملInvited review Are Ca channels targets of praziquantel action?
Praziquantel is the current drug of choice for the control of schistosomiasis. It is highly effective against all species of schistosomes and shows minimal adverse effects. Though introduced for the treatment of schistosomiasis more than 20 years ago, the mode of action of praziquantel remains to be elucidated. This review will focus on advances in defining the molecular target of praziquantel ...
متن کاملSeizures and praziquantel. A case report.
SUMMARY A 2 7 yearjOl d mal e develope d seizure s afte r receivin g a singl e 2 0 mg/k g dos e of praziquante l fo r th e treatmen t o f a n intestina l Hymenolepi s nan a infection. O n further clinica l an d laboratoria l evaluations , h e wa s foun d t o suffe r fro m a n unti l then asymptomati c parenchyma l brai n cysticercosis. Praziquantel must b e use d wit h caution i n thos e areas ...
متن کاملPraziquantel therapy in neurocysticercosis.
Neurocysticercosis is being recognised more often now, because of advances in radio-imaging. No treatment was available for this disease till about a decade back. Praziquantel has provided new hope. From India, there are very few published reports on experience with this drug. Nine cases of neurocysticercosis are being presented, where praziquantel therapy has been tried. Five patients with tum...
متن کاملA Schistosomiasis Model with Praziquantel Resistance
A compartmental model is established for schistosomiasis with praziquantel resistance. The model considers the impact of genetic resistance and drug treatment on the transmission of schistosomiasis. We calculate the basic reproductive number and discuss the existence and stability of disease-free equilibrium, boundary equilibrium, and coexistence equilibrium. Our analysis shows that regardless ...
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ژورنال
عنوان ژورنال: Journal of Veterinary Science & Technology
سال: 2014
ISSN: 2157-7579
DOI: 10.4172/2157-7579.1000200